News
7 May 2025
G protein-coupled receptors (GPCRs) are pivotal in transmitting signals across cell membranes, making them essential targets in biomedical research and drug development. Confocal fluorescence microscopy imaging […]
23 April 2025
What Is Förster Resonance Energy Transfer (FRET) and How Does It Work? Förster Resonance Energy Transfer, or Fluorescence Resonance Energy Transfer (FRET), is a non-radiative, distance-dependent […]
9 April 2025
What Is High-Throughput Screening? High-throughput screening (HTS) is a starting point to discover a new drug candidate. This method is used primarily in the early stages […]
27 March 2025
The development of new therapeutics depends on the ability to identify compounds that interact with specific molecular targets involved in disease pathways. Target-based screening has become […]
4 March 2025
The field of drug discovery faces a critical challenge: despite their vast therapeutic potential, many G Protein-Coupled Receptors (GPCRs) remain unexplored. These receptors play a fundamental […]
21 February 2025
Studying receptor-ligand interaction is a crucial approach in drug discovery and biomedical research. Radioligands have been the gold standard for binding assays since their first use […]
16 January 2024
We are very proud to present our last paper in collaboration with the Institute of Neuroscience of the Universitat de Barcelona, the CiQUS – Center for Research in […]
18 October 2023
Sigma (σ) receptor subtypes, σ1 and σ2, are targets of wide pharmaceutical interest. σ1 receptor ligands are under evaluation in clinical trials for the treatment of diseases such as […]
11 September 2023
A major bottleneck in drug discovery, particularly when targeting transmembrane proteins such as G-coupled receptor proteins (GPCRs), is the challenge of replicating in vitro the precise microenvironment conditions […]