7 May 2025
Applications of Fluorescent Probes in Confocal GPCR imaging: guide for researchers

Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells

G protein-coupled receptors (GPCRs) are pivotal in transmitting signals across cell membranes, making them essential targets in biomedical research and drug development. Confocal fluorescence microscopy imaging […]
23 April 2025
Förster Resonance Energy Transfer (FRET): A Powerful Tool for Fluorescent Probe-Based Live-Cell Imaging

Förster Resonance Energy Transfer (FRET): A Powerful Tool for Fluorescent Probe-Based Live-Cell Imaging

What Is Förster Resonance Energy Transfer (FRET) and How Does It Work? Förster Resonance Energy Transfer, or Fluorescence Resonance Energy Transfer (FRET), is a non-radiative, distance-dependent […]
9 April 2025
Fluorescent Probes for High-Throughput Screening in Drug Discovery

Fluorescent Probes for High-Throughput Screening: A Cost-Effective Alternative to Radioligands in Preclinical Research

What Is High-Throughput Screening? High-throughput screening (HTS) is a starting point to discover a new drug candidate. This method is used primarily in the early stages […]
27 March 2025
Fluorescent Ligands in Fluorescence Polarization Assays

Fluorescent Ligands in Fluorescence Polarization Assays: A Game-Changer for GPCR Drug Discovery

The development of new therapeutics depends on the ability to identify compounds that interact with specific molecular targets involved in disease pathways. Target-based screening has become […]
4 March 2025
Advantages of fluorescent probes in GPCR assays

Advantages of Fluorescent Probes in GPCR Assays

The field of drug discovery faces a critical challenge: despite their vast therapeutic potential, many G Protein-Coupled Receptors (GPCRs) remain unexplored. These receptors play a fundamental […]
21 February 2025
radioligands vs fluorescent ligands

Radioligands vs. Fluorescent Ligands: Binding Assays

Studying receptor-ligand interaction is a crucial approach in drug discovery and biomedical research. Radioligands have been the gold standard for binding assays since their first use […]
16 January 2024

Celtarys develops a new FRET based assay in collaboration with CiQUS and CiMUS

We are very proud to present our last paper in collaboration with the Institute of Neuroscience of the Universitat de Barcelona, the CiQUS – Center for Research in […]
18 October 2023

Celtarys expands its catalogue of receptor ligands with the first commercially available red-emitting fluorescent σ1/σ2 ligands

Sigma (σ) receptor subtypes, σ1 and σ2, are targets of wide pharmaceutical interest. σ1 receptor ligands are under evaluation in clinical trials for the treatment of diseases such as […]
11 September 2023

Celtarys and G.CLIPS join forces to revolutionize transmembrane proteins characterization in drug discovery. 

A major bottleneck in drug discovery, particularly when targeting transmembrane proteins such as G-coupled receptor proteins (GPCRs), is the challenge of replicating in vitro the precise microenvironment conditions […]