23 December 2025
HCS to overcome controlled substance barriers

Overcoming Controlled Substance Barriers in Cannabinoid Receptor Drug Discovery with High-Content Screening

How high-content screening enables cannabinoid receptor research while avoiding controlled substance restrictions and improving assay scalability.
16 December 2025
high content screening with CB2

High-Content Screening Applied to CB₂ Cannabinoid Receptor Ligand Binding

High-content screening enables precise CB2 receptor binding analysis in preclinical research using advanced imaging, quantification, and assay tools.
11 November 2025
Cell Painting in High‑Content Screening

Cell Painting in High‑Content Screening: Limitations and the Rise of Fluorescent Ligands as a Scalable Alternative

How fluorescent ligands offer a scalable, specific alternative to cell painting in high-content screening workflows.
28 October 2025
Design robust high-content screening (HCS) assays

Designing High‑Content Screening (HCS) Assays: Strategies to Overcome Limitations

How to design robust high-content screening (HCS) assays, avoid artifacts and batch effects, and improve drug discovery results.
7 October 2025
Cannabinoid Receptor Binding and Assay Tools

Cannabinoid Receptor Pharmacology: Binding Mechanisms, Brain Targets, and Assay Strategies

Cannabinoid receptor function, brain targets, and antagonist assay strategies in drug discovery.
29 September 2025
GLP‑1 Receptor Agonist

Understanding GLP‑1 Receptor Agonist Mechanisms: From Preclinical Fluorescent Assays to Drug Action

GLP‑1 receptor agonists’ mechanisms and how fluorescent assays enhance preclinical drug discovery.
11 September 2025
Sigma-1 receptor

Targeting Sigma-1 Receptor (σ1R) with Fluorescent Ligands: Advancing Assay Design in CNS Drug Discovery

Sigma receptor 1 in CNS disorders and drug discovery. Discover how targeted assays and fluorescent ligands enhance selectivity and therapeutic potential.
28 August 2025
Biotinylated Fluorophores

Biotinylated Fluorophores: Enhancing Signal Detection and Specificity

How biotinylated fluorophores and fluorescent labeling enhance ligand binding assays by improving signal detection and specificity.
14 August 2025
Biochemical assays for kinase activity in drug discovery

Optimizing Biochemical Assays for Kinase Activity in Drug Discovery

How biochemical assays enhance kinase activity detection in drug discovery. Assay formats, fluorescent ligands, and pathway insights for R&D success.