Muscarinic Receptors

Our potent hM1/hM2 Muscarinic receptor fluorescent antagonist shows high affinity for hM1 and hM2 Muscarinic receptors (Ki =57.77 nM and 37,7 nM respectively in radioligand binding assay). It allows to perform cell visualization in confocal microscopy and high content system experiments as a valid alternative to radioligand binding assays. It is potentially suitable for other fluorescence-based assays.