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Our potent Sigma h σ1/σ2 receptor fluorescent ligand is available in a 10ug vial, allowing you to prepare 103 ml of 100nM working solution to test σ1/σ2 receptors. Our CELT-483 product has been specifically designed to meet the needs of researchers in a variety of fields, enabling the study of σ1 and σ2 receptors with accuracy and precision. It has been validated in flow cytometry (Kd=13,59 nM for σ2) and confocal microcopy in MCF7 cell lines (see publication for more details) to study both σ1 and σ2 receptors, using the appropriate masking agent.
We also provide kits of CELT-483 together with potent and selective σ1 and σ2 receptors masking agents (L6 and F390, respectively).