C5a Receptor

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  • CELT- 58 C5a receptor fluorescent antagonist (646/662)

    10ug vial that allows to prepare 87ml of 100nM working solution to test C5aR.

    Working concentration might differ among assay designs.

    432,00

    Our potent C5a receptor fluorescent antagonist shows high affinity for the C5aR (EC50 = 24.89 nM by saturation binding in Chem1 transfected cells), good potency (KB= 5.8 μM by calcium flux assay) and good competition with the endogenous ligand C5a. It has been validated in flow cytometry competition binding assays using Chem1 transfected cells. It is potentially suitable for other fluorescence-based assays.

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