CELTARY & NANOTEMPER-Discovery partnership to enhance performance in GPCR characterization

Celtarys expands its presence in the GPCR field, developing new applications in collaboration agreement with Nanotemper, a company devoted to the development of innovative instruments for biophysical characterization in early-phase drug discovery.

Thanks to the collaboration between Celtarys and Nanotemper, in this New Application note, we have successfully measured the affinity of the Adenosine 2A receptor in a competitive binding assay. By combining the Monolith X (Nanotemper) and the fluorescent ligand CELT-300 (Celtarys) in the cell membrane extract, we determined the binding affinity of the A2A receptor.