Science Highlights

11 November 2025
Cell Painting in High‑Content Screening

Cell Painting in High‑Content Screening: Limitations and the Rise of Fluorescent Ligands as a Scalable Alternative

How fluorescent ligands offer a scalable, specific alternative to cell painting in high-content screening workflows.
28 October 2025
Design robust high-content screening (HCS) assays

Designing High‑Content Screening (HCS) Assays: Strategies to Overcome Limitations

How to design robust high-content screening (HCS) assays, avoid artifacts and batch effects, and improve drug discovery results.
7 October 2025
Cannabinoid Receptor Binding and Assay Tools

Cannabinoid Receptor Pharmacology: Binding Mechanisms, Brain Targets, and Assay Strategies

Cannabinoid receptor function, brain targets, and antagonist assay strategies in drug discovery.
29 September 2025
GLP‑1 Receptor Agonist

Understanding GLP‑1 Receptor Agonist Mechanisms: From Preclinical Fluorescent Assays to Drug Action

GLP‑1 receptor agonists’ mechanisms and how fluorescent assays enhance preclinical drug discovery.
11 September 2025
Sigma-1 receptor

Targeting Sigma-1 Receptor (σ1R) with Fluorescent Ligands: Advancing Assay Design in CNS Drug Discovery

Sigma receptor 1 in CNS disorders and drug discovery. Discover how targeted assays and fluorescent ligands enhance selectivity and therapeutic potential.
28 August 2025
Biotinylated Fluorophores

Biotinylated Fluorophores: Enhancing Signal Detection and Specificity

How biotinylated fluorophores and fluorescent labeling enhance ligand binding assays by improving signal detection and specificity.
14 August 2025
Biochemical assays for kinase activity in drug discovery

Optimizing Biochemical Assays for Kinase Activity in Drug Discovery

How biochemical assays enhance kinase activity detection in drug discovery. Assay formats, fluorescent ligands, and pathway insights for R&D success.
24 July 2025
Biochemical Assays in Drug Discovery

Biochemical Assays in Drug Discovery: From Target Validation to Therapeutic Development

Biochemical assays drive drug discovery from target validation to therapeutic development. Discover assay formats, examples, and key optimization strategies.
10 July 2025
Targeting GPCRs in Neuroscience

Targeting GPCRs in Neuroscience: Advances in Drug Discovery Strategies

Explore how GPCRs in neuroscience are reshaping drug discovery. Understand new targets, pathways, and the impact of fluorescent ligands in therapeutic innovation.