Science Highlights

23 April 2025
Förster Resonance Energy Transfer (FRET): A Powerful Tool for Fluorescent Probe-Based Live-Cell Imaging

Förster Resonance Energy Transfer (FRET): A Powerful Tool for Fluorescent Probe-Based Live-Cell Imaging

What Is Förster Resonance Energy Transfer (FRET) and How Does It Work? Förster Resonance Energy Transfer, or Fluorescence Resonance Energy Transfer (FRET), is a non-radiative, distance-dependent […]
9 April 2025
Fluorescent Probes for High-Throughput Screening in Drug Discovery

Fluorescent Probes for High-Throughput Screening: A Cost-Effective Alternative to Radioligands in Preclinical Research

What Is High-Throughput Screening? High-throughput screening (HTS) is a starting point to discover a new drug candidate. This method is used primarily in the early stages […]
27 March 2025
Fluorescent Ligands in Fluorescence Polarization Assays

Fluorescent Ligands in Fluorescence Polarization Assays: A Game-Changer for GPCR Drug Discovery

The development of new therapeutics depends on the ability to identify compounds that interact with specific molecular targets involved in disease pathways. Target-based screening has become […]
4 March 2025
Advantages of fluorescent probes in GPCR assays

Advantages of Fluorescent Probes in GPCR Assays

The field of drug discovery faces a critical challenge: despite their vast therapeutic potential, many G Protein-Coupled Receptors (GPCRs) remain unexplored. These receptors play a fundamental […]
21 February 2025
radioligands vs fluorescent ligands

Radioligands vs. Fluorescent Ligands: Binding Assays

Studying receptor-ligand interaction is a crucial approach in drug discovery and biomedical research. Radioligands have been the gold standard for binding assays since their first use […]
19 July 2023

Celtarys extends its chemical conjugation technology to the development of new fluorescent ligands for E3 Ubiquitin ligases

Traditional pharmacological mechanisms leave a significant part of the genome ‘undruggable’, due to the inability to induce or block their activity using agonists and antagonists. Thanks […]
13 July 2023

CELTARY & NANOTEMPER-Discovery partnership to enhance performance in GPCR characterization

Celtarys expands its presence in the GPCR field, developing new applications in collaboration agreement with Nanotemper, a company devoted to the development of innovative instruments for […]
10 July 2023

Transform your biosensor into an innovative technology

The fabrication of a particular device depends heavily on the immobilization of the biosensing element (a probe such as an antibody, aptamer, etc.) onto the transducer […]
27 March 2023

New article showcasing Celtarys  fluorescent ligand for Dopamine D3 Receptor in Fluorescence based HTS

Celtarys Research collaborates with several research groups in Europe for the validation of our products in different assays commonly used in drug discovery, always with the […]