Identifying new E3 Ubiquitin ligase ligands for new PROTACs design is a key element that can improve selective proteasomal-dependent degradation of proteins of interest involved in many pathological processes such as cancer, chronic anaemia, and ischemia.
Our fluorescent probes for VHL and CRBN E3 ligase are powerful tools both for compound screening for new E3ligase ligands and for PROTACs analysis, suitable for in vitro microscopy, binding assays such as TR-FRET competition assays.
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CELT-050 VHL E3 ligase fluorescent ligand (646/662)
For research use only10 µg vial can be used to prepare 66.23 µL of a 100 µM stock solution, providing enough volume for 6 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.
476,00€View moreProduct on backorder. Contact us at info@celtarys.com for an estimated delivery date.
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