8 July 2026
VHL, CRBN and Emerging Ligases like DCAF

VHL, CRBN, and Emerging Ligases like DCAF: Selecting E3 Ligase Handles for PROTAC Drug Discovery

VHL, CRBN and emerging E3 ligases like DCAF: compare handles for your PROTAC program and run fluorescence-based binding assays with ready-to-use kits.
19 July 2023

Celtarys extends its chemical conjugation technology to the development of new fluorescent ligands for E3 Ubiquitin ligases

Traditional pharmacological mechanisms leave a significant part of the genome ‘undruggable’, due to the inability to induce or block their activity using agonists and antagonists. Thanks […]
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