fluorescent ligands

30 March 2026
Measuring Receptor Binding Kinetics and Residence Time Using Fluorescent Ligands

Measuring Receptor Binding Kinetics and Residence Time Using Fluorescent Ligands in GPCR Drug Discovery

Fluorescent ligands have become powerful tools for measuring receptor binding kinetics and residence time in GPCR drug discovery. Unlike traditional radioligand approaches, fluorescence-based methods enable real-time, […]
11 September 2025
Sigma-1 receptor

Targeting Sigma-1 Receptor (σ1R) with Fluorescent Ligands: Advancing Assay Design in CNS Drug Discovery

Sigma receptor 1 in CNS disorders and drug discovery. Discover how targeted assays and fluorescent ligands enhance selectivity and therapeutic potential.
30 June 2025
GPCR Target Identification in Drug Discovery with Fluorescent Ligands

Accelerating GPCR Target Identification in Drug Discovery with Fluorescent Ligands

GPCR and drug discovery: how fluorescent ligands streamline target identification for faster, more accurate screening.
21 February 2025
radioligands vs fluorescent ligands

Radioligands vs. Fluorescent Ligands: Binding Assays

Studying receptor-ligand interaction is a crucial approach in drug discovery and biomedical research. Radioligands have been the gold standard for binding assays since their first use […]
16 January 2024

Celtarys develops a new FRET based assay in collaboration with CiQUS and CiMUS

We are very proud to present our last paper in collaboration with the Institute of Neuroscience of the Universitat de Barcelona, the CiQUS – Center for Research in […]
18 October 2023

Celtarys expands its catalogue of receptor ligands with the first commercially available red-emitting fluorescent σ1/σ2 ligands

Sigma (σ) receptor subtypes, σ1 and σ2, are targets of wide pharmaceutical interest. σ1 receptor ligands are under evaluation in clinical trials for the treatment of diseases such as […]
19 July 2023

Celtarys extends its chemical conjugation technology to the development of new fluorescent ligands for E3 Ubiquitin ligases

Traditional pharmacological mechanisms leave a significant part of the genome ‘undruggable’, due to the inability to induce or block their activity using agonists and antagonists. Thanks […]
13 July 2023

CELTARYS & NANOTEMPER-Discovery partnership to enhance performance in GPCR characterization

Celtarys expands its presence in the GPCR field, developing new applications in collaboration agreement with Nanotemper, a company devoted to the development of innovative instruments for […]
27 January 2023

The advantages to using fluorescence vs radioactivity in receptors kinetic and binding assays.

WHY IS IMPORTANT TO CONSIDER MULTIPLE ASSAY TYPES FOR TARGETS CHARACTERIZATION? Usually, in the identification of new drug-like molecules for a target of interest it is […]