GPCR Fluorescent Ligands

Fluorescent GPCR ligands are among the most versatile tools for studying ligand behavior. They can be applied at multiple stages of the drug discovery process, from target identification to preclinical evaluation. This versatility enables researchers to extract a wide range of information through different experimental setups, including binding affinity assays, receptor localization studies, and receptor internalization analyses.

At Celtarys we have developed an ample catalogue of fluorescent ligands binding to different GPCR families, each with their own fluorescent tag and selectivity, providing a robust and sensitive alternative to traditional radioactive binding assays and excellent signaling in microscopic studies.