Sigma (σ) receptor subtypes, σ1 and σ2, are important pharmaceutical targets for diseases like Alzheimer's, Huntington's, neuropathic pain, and cancer. Despite significant interest, there is a lack of commercial tools to study them.
Sigma (σ) receptor subtypes, σ1 and σ2, are important pharmaceutical targets for diseases like Alzheimer's, Huntington's, neuropathic pain, and cancer. Despite significant interest, there is a lack of commercial tools to study them.
To address this, Celtarys has partnered with the University “Aldo Moro” of Bari to commercialize CELT-483, a fluorescent ligand that binds to both σ1 and σ2 receptors, developed by research group of Prof. Carmen Abate. CELT-483 has been validated in various fluorescence assays (like flow cytometry and confocal microscopy), and Celtarys also offers kits with selective masking agents for σ1 and σ2 receptors.
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CELT-483 sigma hσ1/σ2 receptors fluorescent ligand (646/662)
For research use only10 µg vial can be used to prepare 95.03 µL of a 100 µM stock solution, providing enough volume for 9 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.
476,00€ View more -
BOX OFFER – CELT-483 with masking agents
For research use only10 µg vial can be used to prepare 95.03 µL of a 100 µM stock solution, providing enough volume for 9 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.
539,00€ View more
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