LUXendin762 GLP1 receptor (GLP1R) fluorescent antagonist (762/784) (CELT-113)
27 September 2021
CELT-130 hα1 adrenergic receptor fluorescent antagonist (646/662)
4 October 2022

CELT-175 hD2 Dopamine receptor fluorescent antagonist (748/776)

10ug vial that allows to prepare 1000ml of 100nM working solution to test D2R.

Working concentration might differ among assay designs


Our potent and selective hD2 Dopamine receptor fluorescent antagonist shows high affinity for hD2 receptor and selectivity over the other receptor subtypes (Ki =3.15 nM for hD2 receptor and Ki =294.6 nM and Ki =220.3 nM for D3 and D4 receptor, respectively, in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.