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E3 Ligase Ligands
CELT-050 VHL E3 ligase fluorescent ligand (646/662) For research use only

The figure shows how increasing concentrations of VH298 compete with CELT-050 ligand and thereby prevent TR-FRET from occurring.

Our potent CELT-050 VHL E3 ligase fluorescent ligand is a tracer for VHL E3 ligases binding assays, designed to perform affinity binding curves to VHL protein using TR-FRET homogenous technology.

Von Hippel–Lindau protein (VHL) is the substrate recognition subunit of an E3 ligase recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a targeted protein.

CELT-050 VHL E3 ligase fluorescent ligand (646/662)
_{For research use only}

Name: CELT-050 VHL E3 ligase fluorescent ligand (646/662) For research use only - Celtarys
Price: 476.00 EUR
Availability: InStock

10 µg vial can be used to prepare 66.23 µL of a 100 µM stock solution, providing enough volume for 6 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.

476,00€

Product on backorder. Contact us at info@celtarys.com for an estimated delivery date.

Available on back-order

Category: E3 Ligase Ligands

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CELT-050 VHL E3 ligase fluorescent ligand (646/662) For research use only

10 µg vial can be used to prepare 66.23 µL of a 100 µM stock solution, providing enough volume for 6 assays at a working concentration of 100 nM.Please note that the required concentration may vary depending on the specific assay design.

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CELT-050 VHL E3 ligase fluorescent ligand (646/662)
_{For research use only}

10 µg vial can be used to prepare 66.23 µL of a 100 µM stock solution, providing enough volume for 6 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.

CELT-077 CRBN E3 ligase fluorescent ligand (589/616)
_{For research use only}

10 µg vial can be used to prepare 92.34 µL of a 100 µM stock solution, providing enough volume for 9 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.

CELT-081 CRBN E3 ligase fluorescent ligand (646/662)
_{For research use only}

10 µg vial can be used to prepare 78.78 µL of a 100 µM stock solution, providing enough volume for 7 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.

CELT-504 VHL E3 ligase fluorescent ligand (564/570)
_{For research use only}

10 µg vial can be used to prepare 93.81 µL of a 100 µM stock solution, providing enough volume for 9 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.