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Our potent C5a receptor fluorescent antagonist shows high affinity for the C5aR (EC50 = 24.89 nM by saturation binding in Chem1 transfected cells), good potency (KB = 5.8 μM by calcium flux assay) and good competition with the endogenous ligand C5a. It has been validated in flow cytometry competition binding assays using Chem1 transfected cells. It is potentially suitable for other fluorescence-based assays.
CELT-058 C5a receptor fluorescent antagonist (646/662)
For research use only
10 µg vial can be used to prepare 87.32 µL of a 100 µM stock solution, providing enough volume for 8 assays at a working concentration of 100 nM.
Please note that the required concentration may vary depending on the specific assay design.
476,00€
Product on backorder. Contact us at info@celtarys.com for an estimated delivery date.
Available on back-order