Products

Our ligands’ value:

  • Potent (Ki < 100 nM) and subtype selective ( > 500-fold).
  • Their fluorophores are stable, guarantee their affinity and display a variety of photo-physical properties that meet the market demand for several applications from competitive binding assays to microscopy
  • Their pharmacophores are representative of the target and aligned with international standards
  • Their spacers allow optimal target recognition and placing of the fluorophore in the outer region of the membrane.

Showing 16–20 of 20 results

  • CELT-402

    Potent h5HT2A/5HT2C Serotonin receptor fluorescent antagonist (589/616)

    Our h5HT2A/5HT2C Serotonin receptor fluorescent antagonist shows a high affinity for h5HT2A/h5HT2C serotonin receptors (Ki =29.7 nM and 14.6 nM respectively in radioligand binding assay).It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.

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  • CELT- 211

    Potent and selective h5HT2B Serotonin receptor fluorescent ligand (589/616)

    Our h5HT2B Serotonin receptor fluorescent ligand shows a high affinity for 5HT2B serotonin receptor and high selectivity over the other receptor subtypes (Ki =56.32 nM for 5HT2B receptor in radioligand binding assay).It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.

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  • CELT-335

    Potent hCB1/CB2 Cannabinoids receptors fluorescent ligand (646/662)

    Our hCB cannabinoids receptors fluorescent ligand shows high affinity for hCB1/CB2 cannabinoids receptor (Ki =44.8 nM and 7.4 nM , respectively in radioligand binding assay). It has been validated in High Content Screening assays and it is suitable also for HTRF binding assays as a valid alternative to radioligand binding assays. It allows to perform cell visualization in fluorescence microscopy and it is potentially suitable for other fluorescence-based assays.

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  • CELT331

    Potent and selective hCB2 Cannabinoids receptors fluorescent ligand (646/662)

    Our hCB2 cannabinoids receptor fluorescent ligand shows high affinity for hCB2 cannabinoids receptor and selectivity over hCB1 (Ki =75.9 nM for hCB2 receptor in radioligand binding assay). It is suitable for HTRF binding assays as a valid alternative to radioligand binding assays. It allows to perform cell visualization in fluorescence microscopy, confocal and high content system experiments. It is potentially suitable for other fluorescence-based assays.

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  • CELT-195

    Potent hM1 Muscarinic receptor fluorescent antagonist (748/776)

    Our hM1 Muscarinic receptor fluorescent antagonist shows high affinity for M1 Muscrinic receptor (Ki =57.77 nM in radioligand binding assay). It allows to perform cell visualization in confocal microscopy and high content system experiments as a valid alternative to radioligand binding assays. It is potentially suitable for other fluorescence-based assays.

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