15 July 2021
15 July 2021


Potent and partially selective hD3 Dopamine receptor fluorescent ligand (560/571)

Our hD3 Dopamine receptor fluorescent ligandshows high affinity for hD2 receptor and partial selectivity over the other receptor subtypes (Ki =65.6 nM for hD3 receptor in radioligand binding assay). It has been validated in Fluorescence Polarization binding assays as a valid alternative to radioligand binding assays.It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.


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