Products

CELT-448 hA1 Adenosine receptor fluorescent antagonist (560/571)
15 July 2021
LUXendin551 GLP1 receptor (GLP1R) fluorescent antagonist (551/576) (CELT-111)
27 September 2021

CELT-228 hA3 Adenosine receptor fluorescent antagonist (560/671)

Our potent and selective hA3 Adenosine receptor fluorescent antagonist shows high affinity for hA3 receptor and partial selectivity over the other receptor subtypes (Ki =52.7 nM for hA3 receptor in radioligand binding assay). It has been validated in Fluorescence Polarization binding assays as a valid alternative to radioligand binding assays.It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.

More information and applications

https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00598