24 December 2020
7 January 2021

CELT- 174

Potent and selective hD2 Dopamine receptor fluorescent antagonist (589/616)

Our hD2 Dopamine receptor fluorescent antagonist shows high affinity for hD2 receptor and selectivity over the other receptor subtypes (Ki =1.06 nM for hD2 receptor in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.


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